Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom

Abstract

Bothrops andianus is a venomous snake found in the area of Machu Picchu (Peru). Its venom is not included in the antigenic pool used for production of the Peruvian anti-bothropic anti-venom. B. andianus venom can elicit many biological effects such as hemorrhage, hemolysis, proteolytic activity and lethality. The Peruvian anti-bothropic anti-venom displays consistent cross-reactivity with B. andianus venom, by ELISA and Western Blotting and is also effective in neutralizing the venom's toxic activities.

Description

Keywords

Bothrops andianus, Serpiente andina, Veneno

Citation

Schneider, F. S., Starling, M. C., Duarte, C. G., Machado de Avila, R., Kalapothakis, E., Silva Suarez, W., Tintaya, B., Flores Garrido, K., Seraylan Ormachea, S., Yarleque, A., Bonilla, C., & Chávez-Olórtegui, C. (2012). Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom. Toxicon, 60(6), 1018-1021. https://doi.org/10.1016/j.toxicon.2012.06.018

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